FONDECYT 1210622 | Contribution of peripheral Tau aggregates to Alzheimer´s disease pathogenesis | 2021-2025
Abstract: Recent reports show that Tau aggregates present in the brain of transgenic mice and AD patients can accelerate Tau spreading and downstream pathological cascades when exogenously administered in animal models. This is relevant considering that misfolded tau aggregates correlate with cognitive decline and other pathological features seen in AD. Interestingly, our preliminary data indicates […]
